참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Pyrazole | HCID 1048 | — |
| 반응물 | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 1-Tosylpyrozole | HCID 320750 | 15.3% |
반응 단계
A suspension of pyrazole (1 g) and 4-toluenesulfonyl chloride (2.8 g) in pyridine (10 ml) was stirred at 130° C. for 1 hour. After the reaction mixture was cooled, water was added to the reaction mixture, resulting in a white suspension. The resultant suspension was filtered, and the obtained white solids were washed three times with water. Drying at room temperature under reduced pressure gave white solids (500 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07238720B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_07 |
|---|
| ORD ID | ord-27d2bf1fc6a949e3be428f9784d16fe0 |
|---|
| 출처 메모 | uspto-grants-2007_07 |
|---|
