反应详情

温度

130 °C

A suspension of pyrazole (1 g) and 4-toluenesulfonyl chloride (2.8 g) in pyridine (10 ml) was stirred at 130° C. for 1 hour. After the reaction mixture was cooled, water was added to the reaction mixture, resulting in a white suspension. The resultant suspension was filtered, and the obtained white solids were washed three times with water. Drying at room temperature under reduced pressure gave white solids (500 mg).

1. temperatureAfter the reaction mixture was cooled
2. customresulting in a white suspension
3. filtrationThe resultant suspension was filtered
4. washthe obtained white solids were washed three times with water
5. customDrying at room temperature under reduced pressure