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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1293199생성일: 2026년 10월 26일

Methyl 4-(aminomethyl)benzoate hydrochloride → Methyl 4-[({[2-(4-fluorophenoxy)-5-(trifluoromethyl)pyridin-3-yl]carbonyl}amino)methyl]benzoate

https://huagongshe.com/reaction/1293199

반응식

참여 물질

역할이름HCID투입량
반응물Methyl 4-(aminomethyl)benzoate hydrochlorideHCID 2729253—
반응물2-(4-Fluorophenoxy)-5-(trifluoromethyl)nicotinic acidHCID 57572348—
생성물Methyl 4-[({[2-(4-fluorophenoxy)-5-(trifluoromethyl)pyridin-3-yl]carbonyl}amino)methyl]benzoateHCID 69048049—

반응 단계

The title compound was prepared according to the procedure described in step 3 of Example 1 from 2-(4-fluorophenoxy)-5-(trifluoromethyl)nicotinic acid (step 3) and methyl 4-(aminomethyl)benzoate hydrochloride: 1H-NMR (CDCl3) δ 8.90 (1H, d, J=2.7 Hz), 8.45 (1H, s), 8.01 (2H, d, J=8.2 Hz), 7.43 (2H, d, J=8.2 Hz), 4.78 (2H, d, J=5.9 Hz), 3.90 (3H, s); MS (ESI) m/z 449 (M+H)+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07238714B2
출처 데이터셋uspto-grants-2007_07
ORD IDord-543a57dc490b424e9a3f54ad74f61a70
출처 메모uspto-grants-2007_07