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HRID1293199

反应详情

EQUATION

反应方程式

HRID 1293199 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1ccc(CN)cc1.Cl
HCID2729253

Methyl 4-(aminomethyl)benzoate--hydrogen chloride (1/1)

C9H12ClNO2

结构：O=C(O)c1cc(C(F)(F)F)cnc1Oc1ccc(F)cc1
HCID57572348

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(CNC(=O)c2cc(C(F)(F)F)cnc2Oc2ccc(F)cc2)cc1
HCID69048049

未命名化合物

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 3 of Example 1 from 2-(4-fluorophenoxy)-5-(trifluoromethyl)nicotinic acid (step 3) and methyl 4-(aminomethyl)benzoate hydrochloride: 1H-NMR (CDCl3) δ 8.90 (1H, d, J=2.7 Hz), 8.45 (1H, s), 8.01 (2H, d, J=8.2 Hz), 7.43 (2H, d, J=8.2 Hz), 4.78 (2H, d, J=5.9 Hz), 3.90 (3H, s); MS (ESI) m/z 449 (M+H)+.