Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzylamine → cis-8-Benzoyl-5-benzyl-2-oxa-5,8-diazabicyclo[4.3.0]nonane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzylamine | HCID 7504 | — |
| 반응물 | trans-1-Benzoyl-3-bromo-4-(2-tosyloxyethoxy)-pyrrolidine | HCID 86748810 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | cis-8-Benzoyl-5-benzyl-2-oxa-5,8-diazabicyclo[4.3.0]nonane | HCID 53682667 | — |
반응 단계
124 g (0.265 mol) of trans-1-benzoyl-3-bromo-4-(2-tosyloxyethoxy)-pyrrolidine are re-fluxed overnight with 86 g (0.8 mol) of benzylamine in 1.5 l of xylene. The benzylamine salts are suctioned off and the filtrate concentrated.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05468742 |
| 출처 데이터셋 | uspto-grants-1995_11 |
| ORD ID | ord-c94e862e430e4200978b4d0555fbf93a |
| 출처 메모 | uspto-grants-1995_11 |