HRID129428

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7504

Benzylamine

C7H9N

2 次

结构：Cc1ccc(S(=O)(=O)OCCO[C@@H]2CN(C(=O)c3ccccc3)C[C@H]2Br)cc1

HCID86748810

未命名化合物

PRODUCTS

生成物

结构：O=C(c1ccccc1)N1C[C@H]2OCCN(Cc3ccccc3)[C@H]2C1

HCID53682667

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID7237

o-Xylene

C8H10

PROCEDURE

实验过程

124 g (0.265 mol) of trans-1-benzoyl-3-bromo-4-(2-tosyloxyethoxy)-pyrrolidine are re-fluxed overnight with 86 g (0.8 mol) of benzylamine in 1.5 l of xylene. The benzylamine salts are suctioned off and the filtrate concentrated.

WORKUP

后处理

concentrationthe filtrate concentrated