Hydrochloric Acid → 2-Methyl-5-piperazin-1-yl-benzothiazole hydrochloride

HRID 1294782노트

반응식

HRID 1294782 반응식
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:15]=[CH:16][C:17]3[S:21][C:20]([CH3:22])=[N:19][C:18]=3[CH:23]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:24]>O1CCOCC1>[ClH:24].[CH3:22][C:20]1[S:21][C:17]2[CH:16]=[CH:15][C:14]([N:11]3[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]3)=[CH:23][C:18]=2[N:19]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 589063064-(2-Methyl-benzothiazol-5-yl)-piperazine-1-carboxylic acid tert.-butyl ester

생성물 1

HCID 688959552-Methyl-5-piperazin-1-yl-benzothiazole hydrochloride

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

Prepared in analogy to example 1.6 (d) from 4-(2-methyl-benzothiazol-5-yl)-piperazine-1-carboxylic acid tert.-butyl ester and dioxane saturated with gaseous hydrochloric acid.

출처 및 근거

ORD 기록
ord-96540378ae514c5a9028871d26c3c985
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07241761B2

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