[N:1]1([C:6]2[CH:18]=[CH:17][C:9]([O:10][CH:11]3[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]3)=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[C:19]1(=O)[CH2:24][CH2:23]CCC1.[CH2:26]([Sn](Cl)(Cl)CCCC)CCC.C1([SiH3])C=CC=CC=1>C1COCC1>[N:1]1([C:6]2[CH:7]=[CH:8][C:9]([O:10][CH:11]3[CH2:12][CH2:13][N:14]([CH2:26][CH:24]([CH3:23])[CH3:19])[CH2:15][CH2:16]3)=[CH:17][CH:18]=2)[CH:5]=[CH:4][N:3]=[CH:2]1A solution of the product of Example 6 (130 mg), cyclohexanone (0.06 mL), and dibutyltin dichloride (3 mg) in THF (0.1 mL) was treated with phenylsilane (0.07 mL). After 16 h, the resulting mixture was chromatographed (0–8% 2M methanolic ammonia/DCM), giving the title compound as a waxy solid (18 mg). 1H NMR (400 MHz, CDCl3): 7.75 (t, J=1.2 Hz, 1H), 7.28 (d, J=9.0 Hz, 2H), 7.20 (t, J=1.4 Hz, 1H), 7.18 (t, J=1.2 Hz, 1H), 6.99 (d, J=8.8 Hz, 2H), 4.35–4.27 (m, 1H), 2.76–2.67 (m, 2H), 2.26–2.18 (m, 2H), 2.10 (d, J=7.24 Hz, 2H), 2.05–1.96 (m, 2H), 1.87–1.73 (m, 3H), 0.90 (d, J=6.5 Hz, 6H).
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