Hydrochloric Acid → HCID 22326677, 화합물

HRID 1295581노트

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HRID 1295581 반응식
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([O:14][C:15]2[CH:16]=[CH:17][C:18]3[O:23][CH2:22][C:21](=[O:24])[NH:20][C:19]=3[CH:25]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:26]>ClCCl>[ClH:26].[NH:8]1[CH2:9][CH2:10][CH:11]([O:14][C:15]2[CH:16]=[CH:17][C:18]3[O:23][CH2:22][C:21](=[O:24])[NH:20][C:19]=3[CH:25]=2)[CH2:12][CH2:13]1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 57575834HCID 57575834, 화합물

생성물 1

HCID 22326677HCID 22326677, 화합물수율 88%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

반응 조건

온도
40 °C

실험 절차

A mixture of 6-(1-(tert-butyloxycarbonyl)piperidin-4-yloxy)-4H-benzo[1,4]oxazin-3-one (3.78 g, 10.9 mmol), ethereal hydrogen chloride (50 mL) and dichloromethane (20 mL) was heated at 40° C. for 2 h, then allowed to stir at 20° C. for 18 h. The resulting colourless solid was collected by filtration to give the title compound (2.72 g, 88%).

후처리

  1. filtrationThe resulting colourless solid was collected by filtration

출처 및 근거

ORD 기록
ord-291284446d704972bafe6a199429988c
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07244726B2

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