Hydrochloric Acid → HCID 23105929, 화합물
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([NH:12]C=O)([CH3:11])[CH3:10])=[CH:4][C:3]=1[C:15]([F:18])([F:17])[F:16].Cl.C(=O)([O-])[O-].[K+].[K+]>O>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([NH2:12])([CH3:10])[CH3:11])=[CH:4][C:3]=1[C:15]([F:16])([F:17])[F:18]참가 물질
5
실험 절차
3.30 g (12.5 mmol) N-[2-(4-fluoro-3-trifluoromethyl-phenyl)-1,1-dimethyl-ethyl]-formamide are combined with 25 mL water and 25 mL conc. hydrochloric acid and refluxed for 2 hours. The reaction mixture is diluted with water, made alkaline with potassium carbonate solution and extracted with dichloromethane. The combined organic phases are dried with sodium sulphate and freed from solvent. Brown oil.
후처리
- temperaturerefluxed for 2 hours
- extractionextracted with dichloromethane
- dry with materialThe combined organic phases are dried with sodium sulphate
출처 및 근거
- ORD 기록
- ord-99036bfeb5374e259b7fbebfb6293ad3
- 출처 데이터셋
- uspto-grants-2007_07
- 특허 번호
- US07244728B2
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