Sodium borohydride → HCID 69507792, 화합물

HRID 1295737노트

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HRID 1295737 반응식
[CH3:1][N:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][S:12][CH3:13])[CH:5]=1.[BH4-].[Na+]>CCO>[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][S:12][CH3:13])[CH:5]=1

참가 물질

4

반응물 2

HCID 4311764Sodium borohydrideHCID 69507905828242-89-3

생성물 1

HCID 69507792HCID 69507792, 화합물수율 57%

시약·촉매·용매 1

HCID 702Ethanol용매

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온도
0 °C

실험 절차

Compound from step 2 (3.546 g, 18.16 mmol) was dissolved in EtOH (50 mL) and cooled to 0° C. NaBH4 (859 mg, 22.70 mmol) was added and the mixture was allowed to stir for 4 h. The reaction was carefully quenched with water. The EtOH was removed in vacuo. The aqueous residue was extracted with CH2Cl2. The organic extracts were dried over Na2SO4 and concentrated in vacuo to give 2.044 g (57%) of a clear yellow oil.

후처리

  1. customThe reaction was carefully quenched with water
  2. customThe EtOH was removed in vacuo
  3. extractionThe aqueous residue was extracted with CH2Cl2
  4. dry with materialThe organic extracts were dried over Na2SO4
  5. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-6f44ce3d52c6454cadab13845d9096b1
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07244738B2

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