Triethylamine → Ethyl 3-(4-bromophenylthio)propionate
반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([SH:8])=[CH:4][CH:3]=1.[C:9]([O:13][CH2:14][CH3:15])(=[O:12])[CH:10]=[CH2:11].C(N(CC)CC)C.[OH-].[Na+]>ClCCl>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:11][CH2:10][C:9]([O:13][CH2:14][CH3:15])=[O:12])=[CH:4][CH:3]=1참가 물질
6
실험 절차
To a solution of 10.4 g (55.2 mmol) of 4-bromothiophenol and 6.49 g (55.4 mmol of ethyl acrylate in 5 mL of dichloromethane was added 4.13 g (41 mmol) of triethylamine at 0° C. under argon. The resulting solution was warmed to room temperature and stirred for 12 hours. The solution was then treated with 50 mL 10% aqueous NaOH and the product extracted into 3×100 mL ether.
후처리
- extractionthe product extracted into 3×100 mL ether
출처 및 근거
- ORD 기록
- ord-f9802117dfb34df0bd40699d01fb8eed
- 출처 데이터셋
- uspto-grants-1995_11
- 특허 번호
- US05468879
반응 노트
불러오는 중…