Hydrazine hydrate (1:1) → 4-Chloro-6-(4-phenyl-1H-pyrazol-3-yl)-benzene-1,3-diol

HRID 1296901

반응식

HRID 1296901 반응식
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:5]2=O.O.[NH2:21][NH2:22]>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]([C:5]2[C:6]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[CH:7][NH:22][N:21]=2)[C:9]([OH:8])=[CH:10][C:11]=1[OH:12]

참가 물질

4

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 589136226-Chloro-7-hydroxy-3-phenyl-chromen-4-one

생성물 1

HCID 1785165844-Chloro-6-(4-phenyl-1H-pyrazol-3-yl)-benzene-1,3-diol

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

This compounds was synthesised in the same manner as described above. 6-Chloro-7-hydroxy-3-phenyl-chromen-4-one (0.4 g, 1.47 mmol), hydrazine hydrate (4 ml), ethanol (10 ml). 4-Chloro-6-(4-phenyl-1H-pyrazol-3-yl)-benzene-1,3-diol precipitated out on quenching as a pale yellow (0.37 g, 88%); Rf 0.3 Cf SM 0.7 ethyl acetate/hexane (75/25).

후처리

  1. customThis compounds was synthesised in the same manner
  2. custom4-Chloro-6-(4-phenyl-1H-pyrazol-3-yl)-benzene-1,3-diol precipitated out
  3. customon quenching as a pale yellow (0.37 g, 88%)

출처 및 근거

ORD 기록
ord-e3521520000d415abd2cf97c368c135b
출처 데이터셋
uspto-grants-2007_07
특허 번호
US07247734B2

연결된 노트

불러오는 중…