Hydrochloric Acid → 2-Acetyl-7-(allyloxybutyloxy)fluorene

HRID 130273노트

반응식

HRID 130273 반응식
[C:1]([C:4]1[CH:16]=[CH:15][C:14]2[C:13]3[C:8](=[CH:9][C:10]([OH:17])=[CH:11][CH:12]=3)[CH2:7][C:6]=2[CH:5]=1)(=[O:3])[CH3:2].[CH2:18]([O:21][CH2:22][CH2:23][CH2:24][CH2:25]Cl)[CH:19]=[CH2:20].C(=O)([O-])[O-].[K+].[K+].Cl>CN(C)C=O>[C:1]([C:4]1[CH:16]=[CH:15][C:14]2[C:13]3[C:8](=[CH:9][C:10]([O:17][CH2:25][CH2:24][CH2:23][CH2:22][O:21][CH2:18][CH:19]=[CH2:20])=[CH:11][CH:12]=3)[CH2:7][C:6]=2[CH:5]=1)(=[O:3])[CH3:2]

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 11430Potassium CarbonateHCID 8219132-Acetyl-7-hydroxyfluoreneHCID 137481731-Chloro-4-[(prop-2-en-1-yl)oxy]butane

생성물 1

HCID 692519582-Acetyl-7-(allyloxybutyloxy)fluorene수율 65.5%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
90 °C

실험 절차

2-Acetyl-7-hydroxyfluorene 22.4 g, allyl(4-chlorobutyl) ether 18 g and potassium carbonate 20 g were added to dimethylformamide 150 ml and stirred at 90° C. for 8 hours. The reaction mixture was poured into 6N hydrochloric acid 300 ml to obtain a solid matter. The solid matter was filtered and dried, and then it was recrystallized from ethanol to obtain 22 g of 2-acetyl-7-(allyloxybutyloxy)fluorene. The melting point was 77° C.

후처리

  1. customto obtain a solid matter
  2. filtrationThe solid matter was filtered
  3. customdried
  4. customit was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-9df82e5502bc473eb5ad15896a975d0f
출처 데이터셋
uspto-grants-2008_06
특허 번호
US07381350B2

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