Methyl iodide → 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide
반응식
[CH2:1]([N:3]1[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1)[CH3:2].[CH3:10][I:11]>CC(C)=O>[I-:11].[CH2:1]([N+:3]1([CH3:10])[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1)[CH3:2]참가 물질
4
실험 절차
To a solution of 1-ethyl-4-oxopiperidine (25 g, 0.197 mol) in acetone (250 ml) at RT in a water bath was added methyl iodide (15.5 ml, 0.25 mol) at such a rate to keep the temperature below 30° C. The mixture was filtered and the precipitate washed with acetone and dried to yield 1- ethyl-1-methyl-4-oxopiperidinium iodide (45 g) (LC/MS: Rt 0.38, [M+H]+143).
후처리
- customthe temperature below 30° C
- filtrationThe mixture was filtered
- washthe precipitate washed with acetone
- customdried
출처 및 근거
- ORD 기록
- ord-c1ee797730da4f8fad6f5e4912466d0d
- 출처 데이터셋
- uspto-grants-2008_06
- 특허 번호
- US07385059B2
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