Ethyl Acetate → 3-(S)-(2-(S)-Benzyloxycarbonylamino-4,4-dimethyl-pentanoylamino)-4-(5-fluoro-2,3-dihydro-indol-1-yl)-butyric acid tert-butyl ester

반응식

[C:1]([O:5][C:6](=[O:31])[CH2:7][C@H:8]([NH:20][C:21]([O:23]CC1C=CC=CC=1)=O)[CH2:9][N:10]1[C:18]2[C:13](=[CH:14][C:15]([F:19])=[CH:16][CH:17]=2)[CH2:12][CH2:11]1)([CH3:4])([CH3:3])[CH3:2].[H][H].[C:34](C(C)(C)C)([O:36][CH2:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)=[O:35].CN(C(O[N:56]1N=N[C:58]2C=CC=N[C:57]1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.C(N([CH:78]([CH3:80])[CH3:79])CC)(C)C.[C:81](OCC)(=O)C>[OH-].[OH-].[Pd+2].CN(C=O)C.CO>[C:1]([O:5][C:6](=[O:31])[CH2:7][C@H:8]([NH:20][C:21](=[O:23])[C@@H:57]([NH:56][C:34]([O:36][CH2:37][C:38]1[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=1)=[O:35])[CH2:58][C:78]([CH3:79])([CH3:80])[CH3:81])[CH2:9][N:10]1[C:18]2[C:13](=[CH:14][C:15]([F:19])=[CH:16][CH:17]=2)[CH2:12][CH2:11]1)([CH3:3])([CH3:2])[CH3:4]