Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Chloroethyl chloroformate → 2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Chloroethyl chloroformate | HCID 521305 | — |
| 반응물 | 6-Benzyl-2-(trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine | HCID 57770916 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride | HCID 57445256 | — |
반응 단계
Treatment of the intermediate from Step A above with 1-chloroethyl chloroformate as described for Intermediate 20, Step C afforded the crude title compound. Trituration with ether provided the title compound as a pale orange powder. LC/MS 203.1 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07388019B2 |
| 출처 데이터셋 | uspto-grants-2008_06 |
| ORD ID | ord-49ee30c457a2404fb1fa107faf5b6def |
| 출처 메모 | uspto-grants-2008_06 |