Ethyl formate → HCID 21094283, 화합물

HRID 1350074노트

반응식

HRID 1350074 반응식
Cl.[NH2:2][CH2:3][CH:4]([C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[CH:10]=1)[C:5]([O:7][CH3:8])=[O:6].[CH:17](OCC)=[O:18]>C(OCC)(=O)C>[CH:17]([NH:2][CH2:3][CH:4]([C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([O:15][CH3:16])[CH:10]=1)[C:5]([O:7][CH3:8])=[O:6])=[O:18]

참가 물질

4

반응물 2

HCID 8025Ethyl formateHCID 21094281HCID 21094281, 화합물

생성물 1

HCID 21094283HCID 21094283, 화합물

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

The compound obtained in Step B (20.25 g; 0.08 mol), in the form of a base, is dissolved in 130 ml of ethyl formate (1.81 mol). The reaction mixture is heated at reflux for 6 hours and then evaporated under reduced pressure. The oil obtained is taken up in ethyl acetate. The organic phase is washed with basic water (NaHCO3), dried over magnesium sulphate, filtered and evaporated to yield the title product in the form of a yellow oil.

후처리

  1. temperatureThe reaction mixture is heated
  2. temperatureat reflux for 6 hours
  3. customevaporated under reduced pressure
  4. customThe oil obtained
  5. washThe organic phase is washed with basic water (NaHCO3)
  6. dry with materialdried over magnesium sulphate
  7. filtrationfiltered
  8. customevaporated

출처 및 근거

ORD 기록
ord-5d40ec6490de4f3690e319ecf629a268
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07214689B2

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