Ethyl Acetoacetate → 5-Methyl-1-(1-methyl-piperidin-4-yl)-1H-pyrazole-4-carbaldehyde

HRID 1350757

반응식

HRID 1350757 반응식
C(OCC)(=O)CC(C)=O.[CH3:10][N:11]1[CH2:16][CH2:15][CH:14]([NH:17][NH2:18])[CH2:13][CH2:12]1.[CH:19]1([C:22]2N(C(C)C)N=[CH:24][C:23]=2[CH:30]=[O:31])CC1>>[CH3:19][C:22]1[N:17]([CH:14]2[CH2:15][CH2:16][N:11]([CH3:10])[CH2:12][CH2:13]2)[N:18]=[CH:24][C:23]=1[CH:30]=[O:31]

참가 물질

4

반응물 3

HCID 8868Ethyl AcetoacetateHCID 109205354-Hydrazinyl-1-methylpiperidineHCID 196201355-cyclopropyl-1-(propan-2-yl)-1H-pyrazole-4-carbaldehyde

생성물 1

HCID 210973515-Methyl-1-(1-methyl-piperidin-4-yl)-1H-pyrazole-4-carbaldehyde

실험 절차

5-Methyl-1-(1-methyl-piperidin-4-yl)- 1 H-pyrazole-4-carbaldehyde was prepared from ethyl acetoacetate and (1-methyl-piperidin-4-yl)-hydrazine in the same manner as 5-cyclopropyl-1-isopropyl-1H-pyrazole-4-carbaldehyde (Example 49).

출처 및 근거

ORD 기록
ord-393ace2ea58f4e7aa85f707026a18967
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07214802B2

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