Hydrochloric Acid → (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride

반응식

[OH:1][C@@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][C:9]2[NH:10][C:11](=[O:20])[C:12]3[C:17]([CH:18]=2)=[C:16]([CH3:19])[CH:15]=[CH:14][CH:13]=3)[CH2:3]1.[ClH:21]>>[ClH:21].[OH:1][C@@H:2]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][C:9]2[NH:10][C:11](=[O:20])[C:12]3[C:17]([CH:18]=2)=[C:16]([CH3:19])[CH:15]=[CH:14][CH:13]=3)[CH2:3]1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 10378544(R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one

생성물 1

HCID 68644147(R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride

실험 절차

Using a known method, (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one was converted to a hydrochloride to give (R)-3-[2-(3-hydroxypyrrolidin-1-yl)ethyl]-5-methyl-2H-isoquinolin-1-one hydrochloride.

출처 및 근거

ORD 기록: ord-2ce9e887a4e64cd3a93263dd2fe9816e
출처 데이터셋: uspto-grants-2007_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07220759B2

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