Hydrochloric Acid → 2,4'-Dichloroacetanilide

HRID 1354343

반응식

HRID 1354343 반응식
[Cl:1][CH2:2][C:3](Cl)=[O:4].[Cl:6][C:7]1[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=1.Cl>O1CCOCC1>[Cl:6][C:7]1[CH:13]=[CH:12][C:10]([NH:11][C:3](=[O:4])[CH2:2][Cl:1])=[CH:9][CH:8]=1

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 6577Chloroacetyl chlorideHCID 78124-Chloroaniline

생성물 1

HCID 949202,4'-Dichloroacetanilide

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

3.4 g (30 mol) of 2-chloroacetyl chloride were dissolved in anhydrous dioxane and a solution containing 3.8 g (30 mol) of 4-chloroaniline was added dropwise. After an hour, the batch was poured into ice water, acidified using dilute hydrochloric acid, the supernatant was removed by suction and the residue was washed with water until neutral. The reaction product was recrystallized from ethanol. The yield was 3.2 g.

후처리

  1. additionwas added dropwise
  2. waitAfter an hour
  3. customthe supernatant was removed by suction
  4. washthe residue was washed with water until neutral
  5. customThe reaction product was recrystallized from ethanol

출처 및 근거

ORD 기록
ord-adf3d798277641cc8b923af5e83e894e
출처 데이터셋
uspto-grants-2007_05
특허 번호
US07223781B2

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