Acetic Anhydride → (4-Chloro-6-methylpyridin-2-yl)methyl acetate

HRID 1357030노트

반응식

HRID 1357030 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N+:5]([O-])=[C:4]([CH3:10])[CH:3]=1.[C:11]([O:14]C(=O)C)(=[O:13])[CH3:12]>>[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([CH2:10][O:14][C:11](=[O:13])[CH3:12])[CH:3]=1

참가 물질

3

반응물 2

HCID 7918Acetic AnhydrideHCID 5878434-Chloro-2,6-dimethylpyridine 1-oxide

생성물 1

HCID 18505252(4-Chloro-6-methylpyridin-2-yl)methyl acetate

실험 절차

4.0 g (25.4 mmol) of 4-chloro-2,6-dimethylpyridine-1-oxide was dissolved in 12 ml of acetic anhydride. The resultant solution was gradually heated to raise the temperature to the reflux temperature, and the solution was then stirred overnight at the same temperature. The reacted solution was then condensed under reduced pressure to obtain a crude product of acetic 4-chloro-6-methyl-2-pyridinylmethyl ester.

후처리

  1. temperatureto raise the temperature to the reflux temperature
  2. customcondensed under reduced pressure

출처 및 근거

ORD 기록
ord-b874bf9cc70649c696331d3670e0b7f4
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06589967B1

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