Methyl iodide → Methyl 2-methyl-3-oxopentanoate

HRID 1357179

반응식

HRID 1357179 반응식
CI.[C:3]([O-])([O-])=O.[K+].[K+].[C:9]([CH2:13][C:14]([O:16][CH3:17])=[O:15])(=[O:12])[CH2:10][CH3:11]>CC(C)=O>[CH3:3][CH:13]([C:9](=[O:12])[CH2:10][CH3:11])[C:14]([O:16][CH3:17])=[O:15]

참가 물질

5

반응물 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 121699Methyl 3-oxovalerate

생성물 1

HCID 545860Methyl 2-methyl-3-oxopentanoate

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

Methyl iodide (57 ml) and K2CO3 (127 g) were added to a solution of methyl propionylacetate (100 g) in acetone (800 ml) while cooling on ice. The reaction solution was stirred for 96 hours at room temperature and celite filtered, and then the mother liquor was slowly concentrated under reduced pressure and distilled under reduced pressure to obtain methyl 2-methyl-3-oxopentanoate.

후처리

  1. temperaturewhile cooling on ice
  2. filtrationcelite filtered
  3. concentrationthe mother liquor was slowly concentrated under reduced pressure
  4. distillationdistilled under reduced pressure

출처 및 근거

ORD 기록
ord-d36bac8f934f4ab9af43a8e39619584d
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06589984B1

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