3-Methyl-2-nitroanisole → 2-Methoxy-6-methylaniline

HRID 1358939

반응식

HRID 1358939 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[N+:10]([O-])=O>C(O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[NH2:10]

참가 물질

4

반응물 1

HCID 792913-Methyl-2-nitroanisole

생성물 1

HCID 4592492-Methoxy-6-methylaniline

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 1-methoxy-3-methyl-2-nitrobenzene (15.04 g, 0.09 mol) in ethanol (250 ml) was hydrogenated over 10% palladium on charcoal (4 g) at atmospheric pressure and at room temperature, for 18 h. The catalyst was removed by filtration, and the filtrate evaporated under reduced pressure to leave the title compound (D28) as an amber oil, which crystallised on standing (11.18 g, 91%).

후처리

  1. customThe catalyst was removed by filtration
  2. customthe filtrate evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-6d7e7e529731450082821b906b6e9160
출처 데이터셋
uspto-grants-2003_07
특허 번호
US06599904B2

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