Isopropylamine → 2-Amino-N-isopropylbenzamide

HRID 1362848

반응식

HRID 1362848 반응식
[C:1]12[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[NH:6]C(=O)[O:4][C:2]2=O.[CH:13]([NH2:16])([CH3:15])[CH3:14]>O>[NH2:6][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:1]=1[C:2]([NH:16][CH:13]([CH3:15])[CH3:14])=[O:4]

참가 물질

4

반응물 2

HCID 6363IsopropylamineHCID 8359Isatoic Anhydride

생성물 1

HCID 944112-Amino-N-isopropylbenzamide수율 77.1%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A round-bottomed flask was charged with isatoic anhydride (5.0 g, 0.030 mol) and 30 mL water. Isopropylamine (4.64 mL, 0.049 mol) was added slowly to the reaction mixture. The product precipitated from the reaction mixture. After 1 h, the reaction mixture was filtered and washed with water to give 4.12 g (71% yield) of a white solid

후처리

  1. customThe product precipitated from the reaction mixture
  2. filtrationthe reaction mixture was filtered
  3. washwashed with water

출처 및 근거

ORD 기록
ord-7fc24b27a8664e549d66df96405fa8cf
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07884098B2

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