Cyclohexanone → [2-(3-Butyl-3-cyclohexyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid

HRID 1363693노트

반응식

HRID 1363693 반응식
[CH:1]1([N:7]([CH2:21][CH2:22][C:23]2C=CC=C[CH:24]=2)[C:8](=[O:20])[NH:9][C:10]2[S:11][C:12]([S:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:13][N:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(N)CCC.C1(=O)CCCCC1>C(OC(=O)C)C>[CH2:21]([N:7]([CH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[C:8](=[O:20])[NH:9][C:10]1[S:11][C:12]([S:15][CH2:16][C:17]([OH:19])=[O:18])=[CH:13][N:14]=1)[CH2:22][CH2:23][CH3:24]

참가 물질

5

반응물 3

HCID 7967CyclohexanoneHCID 8007ButylamineHCID 11993791[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acid

생성물 1

HCID 16101127[2-(3-Butyl-3-cyclohexyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid, from n-butylamine, cyclohexanone and 2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-1b5086e3dd464d7b852e46405da91092
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07884210B2

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