Cyclohexanesulfonamide → 2,2-Dimethylpropane-1-sulfonamide

HRID 1365006

반응식

HRID 1365006 반응식
C1([S:7]([NH2:10])(=[O:9])=[O:8])CCCCC1.[CH2:11]([Mg]Cl)[C:12]([CH3:15])([CH3:14])[CH3:13]>C(OCC)C>[CH2:11]([S:7]([NH2:10])(=[O:9])=[O:8])[C:12]([CH3:15])([CH3:14])[CH3:13]

참가 물질

4

반응물 2

HCID 75536CyclohexanesulfonamideHCID 178418809HCID 178418809, 화합물

생성물 1

HCID 183484002,2-Dimethylpropane-1-sulfonamide수율 27%

시약·촉매·용매 1

HCID 3283Diethyl Ether용매

실험 절차

Following the procedure for the preparation of cyclohexylsulfonamide, 49 mL (37 mmol) of 0.75M neopentylmagnesium chloride (Alfa) in diethyl ether was converted to 1.52 g (27%) of the desired product as a white solid. 1H NMR (CDCl3) δ 1.17 (s, 9H), 3.12 (s, 2H), 4.74 (brs, 2H); 13C NMR (CDCl3) δ 29.46, 31.51, 67.38; MS m/e 150 (M−1)−.

출처 및 근거

ORD 기록
ord-80a4c0f6e45e40c887f0c3d28f8e133d
출처 데이터셋
uspto-grants-2011_02
특허 번호
US07888464B2

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