Water → 6-Bromo-3-nitro-2-pyridinamine
반응식
Br[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Br:11])[N:3]=1.[NH4+:12].C(O)C.O>C(O)C>[NH2:12][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[C:4]([Br:11])[N:3]=1참가 물질
5
실험 절차
To a suspension of 2,6-dibromo-3-nitropyridine (5.00 g) in ethanol (10 ml) was added a solution (6.8 M, 15 ml) of ammonium/ethanol at room temperature, and the mixture was stirred at room temperature for 19 hr in a sealed container. Water (25 ml) was added to the reaction mixture, and the precipitate was collected by filtration and washed with ethanol. This was suspended in ethanol (55 ml), heated, and allowed to cool. The precipitate was collected by filtration to give 2-amino-6-bromo-3-nitropyridine as a yellow powder (3.19 g).
후처리
- filtrationthe precipitate was collected by filtration
- washwashed with ethanol
- temperatureheated
- temperatureto cool
- filtrationThe precipitate was collected by filtration
출처 및 근거
- ORD 기록
- ord-cf8c280b8dfd4666ad89c9c8484a8bcb
- 출처 데이터셋
- uspto-grants-2003_06
- 특허 번호
- US06573274B1
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