N-bromobutanimide → HCID 22282008, 화합물

HRID 1368668노트

반응식

HRID 1368668 반응식
[Br:1]N1C(=O)CCC1=O.[CH3:9][O:10][C:11]1[CH:23]=[CH:22][CH:21]=[CH:20][C:12]=1[O:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16]>C(Cl)(Cl)(Cl)Cl>[Br:1][CH:14]([O:13][C:12]1[CH:20]=[CH:21][CH:22]=[CH:23][C:11]=1[O:10][CH3:9])[C:15]([O:17][CH2:18][CH3:19])=[O:16]

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 83114Ethyl (2-methoxyphenoxy)acetate

생성물 1

HCID 22282008HCID 22282008, 화합물수율 105.9%

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A solution of N-bromosuccinimide (13.35 g), azoisobutyronitrile (200 mg) and ethyl 2-(2-methoxyphenoxy)acetate (15.1 g) in anhydrous carbon tetrachloride (ex. calcium hydride) (100 ml) was irradiated with a 120 W sunlamp under reflux and a nitrogen atmosphere for 7 hours. The resulting suspension was allowed to stand at room temperature for 72 hours and was then filtered to remove the suspended solids, which were washed with toluene (40 ml). The combined filtrates were evaporated under vacuum leaving a brown liquid (22 g) Rf 0.75 (dichloromethane).

후처리

  1. temperatureunder reflux
  2. waitto stand at room temperature for 72 hours
  3. filtrationwas then filtered
  4. customto remove the suspended solids, which
  5. washwere washed with toluene (40 ml)
  6. customThe combined filtrates were evaporated under vacuum

출처 및 근거

ORD 기록
ord-2c8b4bb840e84db88511c7b5e5a24f84
출처 데이터셋
uspto-grants-2003_06
특허 번호
US06573270B1

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