Dimethylformamide dimethyl acetal → HCID 54384069, 화합물

반응식

[C:1]([CH2:3][C:4]([C:6]1[S:7][CH:8]=[CH:9][N:10]=1)=[O:5])#[N:2].CO[CH:13](OC)[N:14]([CH3:16])[CH3:15]>>[C:1]([C:3](=[CH:13][N:14]([CH3:16])[CH3:15])[C:4]([C:6]1[S:7][CH:8]=[CH:9][N:10]=1)=[O:5])#[N:2]

참가 물질

반응물 2

HCID 78373Dimethylformamide dimethyl acetal

HCID 185169803-Oxo-3-(1,3-thiazol-2-yl)propanenitrile

생성물 1

HCID 54384069HCID 54384069, 화합물

실험 절차

2-Cyano-3-dimethylamino-1-thiazol-2-ylpropen-1-one was prepared from 2-cyanoacetyl thiazole (400 mg,2.94 mmol) and dimethylformamide dimethylacetal (1.5 mL) as a yellow solid, m.p. 126° δH (CDCl3) 8.89 (1H, s), 7.96 (1H, d, J 3.3 Hz), 7.60 (1H, d, J 3.1 Hz), 3.54 (3H, s) and 3.35 (3H, s).

출처 및 근거

ORD 기록: ord-96dc35b5c5204dc288a1b378faa7c280
출처 데이터셋: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06579983B1

반응 노트

불러오는 중…