1-(Thiophen-3-yl)ethanone → 3-Dimethylamino-1-thien-3-ylpropen-1-one

HRID 1370085

반응식

HRID 1370085 반응식
[C:1]([C:4]1[CH:8]=[CH:7][S:6][CH:5]=1)(=[O:3])[CH3:2].CO[CH:11](OC)[N:12]([CH3:14])[CH3:13]>>[CH3:11][N:12]([CH3:14])[CH:13]=[CH:2][C:1]([C:4]1[CH:8]=[CH:7][S:6][CH:5]=1)=[O:3]

참가 물질

3

반응물 2

HCID 151161-(Thiophen-3-yl)ethanoneHCID 78373Dimethylformamide dimethyl acetal

생성물 1

HCID 5964663-Dimethylamino-1-thien-3-ylpropen-1-one

실험 절차

3-dimethylamino-1-thien-3-ylpropen-1-one was prepared from 3-acetylthiophene (15.0 g) and dimethylformamide dimethylacetal (47.5 mL, 357 mmol) as a yellow solid (14 g), m.p. 98°. δH (CDCl3) 7.90 (1H, dd, J 3.0, 1.0 Hz), 7.76 (1H, d, J 12.4 Hz), 7.53 (1H, dd, J 5.9,1.0 Hz), 7.28-7.25 (1H, m), 5.57 (1H,d, J 12.4 Hz) and 3.03 (6H, bs).

출처 및 근거

ORD 기록
ord-ee06bd1fdb374742ae23ed07826de3d5
출처 데이터셋
uspto-grants-2003_06
특허 번호
US06579983B1

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