Sulfuric Acid → 61706-47-6

HRID 1370251노트

반응식

HRID 1370251 반응식
[N+:1]([C:4]1[CH:19]=[CH:18][C:7]([C:8]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)([CH3:11])[C:9]#[N:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].S(=O)(=O)(O)[OH:21].[OH-].[Na+]>>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([C:8]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)([CH3:11])[C:9]([NH2:10])=[O:21])=[CH:18][CH:19]=1)([O-:3])=[O:2]

참가 물질

4

반응물 3

HCID 1118Sulfuric AcidHCID 14798Sodium HydroxideHCID 2110592-(4-Nitrophenyl)-2-phenylpropanenitrile

생성물 1

HCID 304617961706-47-6

실험 절차

) A mixture of 0.020 mol of p-nitro-α-phenylhydratroponitrile and 28 ml of concentrated sulfuric acid solution (90%) is heated in a water-bath for 3.5 hours. The reaction mixture is poured onto crushed ice, neutralized with a sodium hydroxide solution and the product is extracted with chloroform. The organic layer is washed with water, dried and evaporated in vacuo and the residue is crystallized from either, yielding 2.4 grams of p-nitro-α-phenylhydratropamide. (interm. 7)

후처리

  1. temperatureis heated in a water-bath for 3.5 hours
  2. additionThe reaction mixture is poured
  3. customonto crushed ice
  4. extractionthe product is extracted with chloroform
  5. washThe organic layer is washed with water
  6. customdried
  7. customevaporated in vacuo
  8. customthe residue is crystallized from either,

출처 및 근거

ORD 기록
ord-75f1c2a991374c7083012814ffcee94d
출처 데이터셋
uspto-grants-2003_06
특허 번호
US06583141B1

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