7-Ethylindole → 7-Ethyl-3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indole

HRID 13708

반응식

[CH2:1]([C:3]1(O)[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[CH3:2].[CH2:14]([C:16]1[CH:17]=[CH:18][CH:19]=[C:20]2[C:24]=1[NH:23][CH:22]=[CH:21]2)[CH3:15]>>[CH2:14]([C:16]1[CH:17]=[CH:18][CH:19]=[C:20]2[C:24]=1[NH:23][CH:22]=[C:21]2[C:3]1([CH2:1][CH3:2])[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[CH2:5][CH2:4]1)[CH3:15]

참가 물질

반응물 2

HCID 27247117-Ethylindole

HCID 593404281-Ethyl-5-fluoroindan-1-ol

생성물 1

HCID 116092367-Ethyl-3-(1-ethyl-5-fluoro-indan-1-yl)-1H-indole

실험 절차

Utilizing 1-ethyl-5-fluoro-indan-1-ol and 7-ethylindole, the title compound is prepared as in example 1. 104 mg (58%). LC-MS m/z 308.1 (M++1).

출처 및 근거

ORD 기록: ord-3e93cb96b32848808ec6b450cfcfbdb9
출처 데이터셋: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07728150B2

연결된 노트

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