Methanol → 3-(Allyloxy)phenol
반응식
C([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][CH2:12][CH:13]=[CH2:14])[CH:6]=1)(=O)C.[OH-].[Na+].CO>C1COCC1>[CH2:12]([O:11][C:7]1[CH:6]=[C:5]([OH:4])[CH:10]=[CH:9][CH:8]=1)[CH:13]=[CH2:14]참가 물질
5
실험 절차
The product from Example 61A (7.19 g, 37.4 mmoles) in THF (30 mL) was treated with 4N NaOH (19 mL, 75 mmoles) and MeOH (5 mL). After one hour, the reaction mixture was concentrated under reduced pressure. The residue was dissolved in ethyl acetate, washed with aqueous NH4Cl, brine, dried (Na2SO4), filtered, and the filtrate concentrated under reduced pressure to provide the title compound without further purification.
후처리
- concentrationthe reaction mixture was concentrated under reduced pressure
- dissolutionThe residue was dissolved in ethyl acetate
- washwashed with aqueous NH4Cl, brine
- dry with materialdried (Na2SO4)
- filtrationfiltered
- concentrationthe filtrate concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-83b92bd422474d3b90f45bf086b1dfbf
- 출처 데이터셋
- uspto-grants-2003_06
- 특허 번호
- US06583180B2
반응 노트
불러오는 중…