tert-Butyl 4-{[({[(2S)-4-(3,4-dichlorobenzyl)morpholin-2-yl]methyl}amino)carbonyl]amino}butanoate → 4-{[({[(2S)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}amino)carbonyl]amino}butanoic Acid Hydrochloride
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:27]=[CH:28][C:29]=1[Cl:30])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][C@@H:8]([CH2:12][NH:13][C:14]([NH:16][CH2:17][CH2:18][CH2:19][C:20]([O:22]C(C)(C)C)=[O:21])=[O:15])[CH2:7]1>Cl.O1CCOCC1>[ClH:1].[Cl:1][C:2]1[CH:3]=[C:4]([CH:27]=[CH:28][C:29]=1[Cl:30])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][C@@H:8]([CH2:12][NH:13][C:14]([NH:16][CH2:17][CH2:18][CH2:19][C:20]([OH:22])=[O:21])=[O:15])[CH2:7]1참가 물질
4
반응물 1
생성물 1
시약·촉매·용매 2
실험 절차
Intermediate 25 (0.345 g) was dissolved in 4M hydrogen chloride in dioxane (5 ml), and the mixture was allowed to stand at 22° C. for 19.5 h. The solvent was evaporated in vacuo to give the title compound as a white solid (0.330 g).