1-Methylpiperazine → HCID 21071294, 화합물
반응식
Cl[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]([CH2:12][C:13]([OH:15])=[O:14])[CH:9]=[CH:10][CH:11]=1.[CH3:16][N:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>O>[CH3:16][N:17]1[CH2:22][CH2:21][N:20]([CH2:2][CH2:3][CH2:4][O:5][C:6]2[CH:7]=[C:8]([CH2:12][C:13]([OH:15])=[O:14])[CH:9]=[CH:10][CH:11]=2)[CH2:19][CH2:18]1참가 물질
4
반응 조건
- 온도
- 60 °C
실험 절차
A mixture of 3-(3-chloro-propoxy)-phenylacetic acid (0.5 g, 2.2 mmol) and N-methylpiperazine (1.9 mL) was heated at 60° C. overnight. The reaction was diluted with water and purified by preparative HPLC to give the product as a clear gel. (0.6 g, 94%).
후처리
- custompurified by preparative HPLC
출처 및 근거
- ORD 기록
- ord-865f1d3b290a4c6d8fdfd4e3e66e21e7
- 출처 데이터셋
- uspto-grants-2007_01
- 특허 번호
- US07157476B2
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