3-Nitrodibenzofuran → 3-Dibenzofuranamine
반응식
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=1)([O-])=O>[Ni].C(O)C>[CH:6]1[C:7]2[C:11]3[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=3[O:9][C:8]=2[CH:16]=[C:4]([NH2:1])[CH:5]=1참가 물질
4
실험 절차
Combine 3-nitrodibenzofuran (22.0 g, 0.1 mol) and Raney nickel (2.75 g), and ethanol (365 ml) and hydrogenate at room temperature and 40 psi (276 kPa). After 18 hours, filter and concentrate the filtrate to residue. Chromatograph the residue eluting with 9:1 hexane:EtOAc to give the title compound.
후처리
- customhydrogenate at room temperature
- filtrationfilter
- concentrationconcentrate the filtrate to residue
- washChromatograph the residue eluting with 9:1 hexane
출처 및 근거
- ORD 기록
- ord-9738013b52af4902825d241884ee1d3d
- 출처 데이터셋
- uspto-grants-2007_01
- 특허 번호
- US07157488B2
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