Phosphorus oxychloride → 4-Chloro-2-(methylthio)-5-phenylpyrimidine

반응식

[CH3:1][S:2][C:3]1[N:8]=[C:7](O)[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][N:4]=1.P(Cl)(Cl)([Cl:18])=O>>[CH3:1][S:2][C:3]1[N:8]=[C:7]([Cl:18])[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][N:4]=1

참가 물질

반응물 2

HCID 24813Phosphorus oxychloride

HCID 178503405HCID 178503405, 화합물

생성물 1

HCID 110209004-Chloro-2-(methylthio)-5-phenylpyrimidine

실험 절차

Prepared from 2-methylsulphenyl-4-hydroxy-5-phenyl-pyrimidine by reacting with phosphorus oxychloride at reflux temperature, melting point: 99° C.

후처리

temperatureat reflux temperature, melting point: 99° C.

출처 및 근거

ORD 기록: ord-5d2ea9fe1d664d15b2251f51cf780d22
출처 데이터셋: uspto-grants-2007_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07166599B2

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