Triphenylphosphine → (3-Methoxybenzyl)triphenylphosphonium Chloride

HRID 1374845노트

반응식

HRID 1374845 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][Cl:7].[C:11]1([P:17]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>CN(C)C=O>[Cl-:7].[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][P+:17]([C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)([C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1

참가 물질

4

반응물 2

HCID 11776TriphenylphosphineHCID 699943-Methoxybenzyl chloride

생성물 1

HCID 11407464(3-Methoxybenzyl)triphenylphosphonium Chloride수율 61%

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
150 °C

실험 절차

3-Methoxybenzyl chloride (1.05 g, 6.69 mmol), triphenylphosphine (1.75 g, 6.67 mmol) was dissolved in dimethylformamide (10 ml) and heated at 150° C. for 40 minutes. The reaction mixture was cooled to room temperature, and the solid precipitated was collected by filtration and washed and ethyl ether, and then dried under reduced pressure to obtain the title compound as colorless solid 1.70 g (yield: 61%).

후처리

  1. temperatureThe reaction mixture was cooled to room temperature
  2. customthe solid precipitated
  3. filtrationwas collected by filtration
  4. washwashed
  5. dry with materialethyl ether, and then dried under reduced pressure

출처 및 근거

ORD 기록
ord-dd329a8845a841a2858c3b6ba450995c
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07166617B2

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