Hydrochloric Acid → 5-Amino-2-methoxy-5-methylhex-3-yne hydrochloride

HRID 1374909노트

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HRID 1374909 반응식
[CH3:1][O:2][CH:3]([C:5]#[C:6][C:7]([N:10]1[Si](C)(C)CC[Si]1(C)C)([CH3:9])[CH3:8])[CH3:4].[ClH:19]>>[ClH:19].[NH2:10][C:7]([CH3:9])([CH3:8])[C:6]#[C:5][CH:3]([O:2][CH3:1])[CH3:4]

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 21078409(2-Methoxy-5-methylhex-3-yn-5-yl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane

생성물 1

HCID 210784255-Amino-2-methoxy-5-methylhex-3-yne hydrochloride

실험 절차

(2-Methoxy-5-methylhex-3-yn-5-yl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane (1.2 g) was stirred with dilute aqueous hydrochloric acid (12 ml) for 0.25 hours. The aqueous phase was washed with diethyl ether (twice) and the evaporated under reduced pressure. The residue was evaporated with toluene (twice) to remove residual water to give 5-amino-2-methoxy-5-methylhex-3-yne hydrochloride, 0.54 g, as a yellow solid.

후처리

  1. washThe aqueous phase was washed with diethyl ether (twice) and the
  2. customevaporated under reduced pressure
  3. customThe residue was evaporated with toluene (twice)
  4. customto remove residual water

출처 및 근거

ORD 기록
ord-f4899fa024e248c28d01fcf05223a0e6
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07166621B2

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