Methyl iodide → N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

HRID 1375296노트

반응식

HRID 1375296 반응식
[CH3:1][O:2][CH2:3][CH2:4][N:5]([CH2:8][CH3:9])[CH2:6][CH3:7].[CH3:10][I:11]>O1CCCC1>[I-:11].[CH3:1][O:2][CH2:3][CH2:4][N+:5]([CH2:8][CH3:9])([CH2:6][CH3:7])[CH3:10]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 113555002-methoxyethyldiethylamine

생성물 1

HCID 71374868N,N-Diethyl-2-methoxy-N-methylethan-1-aminium iodide

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Next, 8.2 g of the 2-methoxyethyldiethylamine was dissolved in 10 ml of tetrahydrofuran (Wako Pure Chemical Industries), then 4.0 ml of methyl iodide (Wako Pure Chemical Industries) was added under ice cooling. After 30 minutes, the mixture was removed from the ice bath and stirred overnight at room temperature. The solvent in this reaction solution was subsequently driven off by vacuum distillation, and the resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)—tetrahydrofuran system, yielding 16 g of 2-methoxyethyldiethylmethylammonium iodide.

후처리

  1. customthe mixture was removed from the ice bath
  2. distillationThe solvent in this reaction solution was subsequently driven off by vacuum distillation
  3. customthe resulting solids were recrystallized from an ethanol (Wako Pure Chemical Industries)—tetrahydrofuran system

출처 및 근거

ORD 기록
ord-7e491a2f420843178adf8dd7a970246f
출처 데이터셋
uspto-grants-2007_01
특허 번호
US07167353B2

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