Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-tert-Butyl hydrogen N-((phenylmethoxy)carbonyl)-L-aspartate → Z-Asp(OtBu)-Val-OtBu
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-tert-Butyl hydrogen N-((phenylmethoxy)carbonyl)-L-aspartate | HCID 111082 | — |
| 반응물 | tert-Butyl L-valinate | HCID 114626 | — |
| 반응물 | HCID 15674413 | HCID 15674413 | — |
| 생성물 | Z-Asp(OtBu)-Val-OtBu | HCID 70050186 | — |
반응 단계
A diester such as H-Gly-Asp(OtBu)-Val-OtBu can be prepared by condensing Z-Asp(OtBu)-OH and H-Val-OtBu to give Z-Asp(OtBu)-Val-OtBu, hydrogenolyzing the latter, coupling the resulting H-Asp(OtBu)-Val-OtBu with Z-Gly-OSu to give Z-Gly-Asp(OtBu)-Val-OtBu and hydrogenolyzing the latter.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05663297 |
| 출처 데이터셋 | uspto-grants-1997_09 |
| ORD ID | ord-3c2bf62bcd4640fba426c57d9c71f519 |
| 출처 메모 | uspto-grants-1997_09 |