Dichloromethane → HCID 23682646, 화합물

HRID 1379799노트

반응식

HRID 1379799 반응식
[OH-].[Na+:2].[C:3]([C:5]1[CH:25]=[CH:24][C:8]([C:9]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([CH3:18])=[C:14]([C:19]([O:21]CC)=[O:20])[S:13]2)=[O:10])=[CH:7][CH:6]=1)#[N:4].C(Cl)Cl>CO>[C:3]([C:5]1[CH:25]=[CH:24][C:8]([C:9]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([CH3:18])=[C:14]([C:19]([O-:21])=[O:20])[S:13]2)=[O:10])=[CH:7][CH:6]=1)#[N:4].[Na+:2]

참가 물질

5

반응물 3

HCID 6344DichloromethaneHCID 14798Sodium HydroxideHCID 4249922HCID 4249922, 화합물

생성물 1

HCID 23682646HCID 23682646, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

10% Aqueous sodium hydroxide solution (48 ml) was added to a mixture of ethyl 2-(4-cyanobenzoylimino)-3,4-dimethylthiazoline-5-carboxylate (9.88 g), methylene chloride (250 ml) and methanol (250 ml), followed by stirring at room temperature for 17 hours. The reaction mixture was concentrated under reduced pressure, and the precipitated crystals were collected by filtration to give sodium 2-(4-cyanobenzoylimino)-3,4-dimethylthiazoline-5-carboxylate (10.0 g).

후처리

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. filtrationthe precipitated crystals were collected by filtration

출처 및 근거

ORD 기록
ord-10a66edc96fc466d824e4ad2fd402eae
출처 데이터셋
uspto-grants-1997_09
특허 번호
US05672712

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