Methanol → HCID 136332138, 화합물

HRID 1380311노트

반응식

HRID 1380311 반응식
[OH:1][N:2]=[C:3]([CH3:18])[C:4]([C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH3:16])[C:11](=[O:17])[CH2:10][CH2:9]2)=O.[NH2:19][NH:20][C:21]([NH2:23])=[S:22].CO.O>C(O)(=O)C>[OH:1][N:2]=[C:3]([CH3:18])[C:4]([C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH3:16])[C:11](=[O:17])[CH2:10][CH2:9]2)=[N:19][NH:20][C:21]([NH2:23])=[S:22]

참가 물질

6

반응물 4

HCID 887MethanolHCID 962WaterHCID 2723789ThiosemicarbazideHCID 73666243HCID 73666243, 화합물

생성물 1

HCID 136332138HCID 136332138, 화합물수율 26.2%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A mixture of 6-(2-hydroxyiminopropionyl)-1-methyl-2-oxo-1,2,3,4-tetrahydroquinoline (1 g), thiosemicarbazide (0.48 g), methanol (10 ml), water (5 ml) and acetic acid (0.1 ml) was refluxed for 13 hours with stirring. After cooling, the resulting precipitates were collected by filtration, washed successively with ethanol, water and ethanol, and then dried to give 0.34 g of 6-(2-hydroxyimino-1-thiosemicarbazonopropyl)-1-methyl-2-oxo-1,2,3,4-tetrahydroquinoline.

후처리

  1. temperaturewas refluxed for 13 hours
  2. temperatureAfter cooling
  3. customthe resulting precipitates
  4. filtrationwere collected by filtration
  5. washwashed successively with ethanol, water and ethanol
  6. customdried

출처 및 근거

ORD 기록
ord-cd56ec2356cd43809b308a87e3d511e4
출처 데이터셋
uspto-grants-1986_04
특허 번호
US04581356

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