Nitromethane → 4-Nitro-3-(3,4-dichlorophenyl)butanoic acid methyl ester
반응식
[CH3:1][O:2][C:3](=[O:14])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([Cl:13])[CH:7]=1.[N+:15]([CH3:18])([O-:17])=[O:16].CN(C)C(=N)N(C)C>C(OCC)C.Cl>[CH3:1][O:2][C:3](=[O:14])[CH2:4][CH:5]([C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([Cl:13])[CH:7]=1)[CH2:18][N+:15]([O-:17])=[O:16]참가 물질
6
실험 절차
A mixture of 300 g of 3,4-dichlorocinnamic acid methyl ester, 400 g of nitromethane and 26 g of tetramethylguanidine is allowed to stir for 72 hours. The solution is diluted with ethyl ether and aqueous hydrochloric acid solution (1 N, 1 liter) is added. The organic layer is separated, dried over anhydrous magnesium sulfate, and evaporated to give 4-nitro-3-(3,4-dichlorophenyl)butanoic acid methyl ester.
후처리
- additionis added
- customThe organic layer is separated
- dry with materialdried over anhydrous magnesium sulfate
- customevaporated
출처 및 근거
- ORD 기록
- ord-ded5ca7a3c5548258bdc1166d5a20a7e
- 출처 데이터셋
- uspto-grants-1986_04
- 특허 번호
- US04584313
반응 노트
불러오는 중…