1-Butanol → N,N-dimethyl-N'-(2,3-dihydrobenzofuran-2-ylmethyl)-1,3-propanediamine

HRID 1381538노트

반응식

HRID 1381538 반응식
S([C:5]1[CH:11]=[CH:10][C:8]([CH3:9])=[CH:7][CH:6]=1)([O-])(=O)=O.[CH3:12][N:13]([CH3:18])[CH2:14][CH2:15][CH2:16][NH2:17].[CH2:19]([OH:23])[CH2:20]CC>>[CH3:12][N:13]([CH3:18])[CH2:14][CH2:15][CH2:16][NH:17][CH2:20][CH:19]1[CH2:9][C:8]2[CH:7]=[CH:6][CH:5]=[CH:11][C:10]=2[O:23]1

참가 물질

4

반응물 3

HCID 2631-ButanolHCID 7993N,N-Dimethyl-1,3-propanediamineHCID 85570p-Toluenesulfonate2회

생성물 1

HCID 14099475N,N-dimethyl-N'-(2,3-dihydrobenzofuran-2-ylmethyl)-1,3-propanediamine

실험 절차

Finally, 23.5 g (0.075 mol) of the above tosylate and 38.6 g (0.378 mol) of 3-(dimethylamino)propylamine were suspended in 150 ml of butanol, and the mixture was brought to reflux until the tosylate had disappeared.

출처 및 근거

ORD 기록
ord-dc2673a0945143cc9b81d177e7e27f7a
출처 데이터셋
uspto-grants-1989_02
특허 번호
US04803219

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