Cyanide → 2-(4-Hydroxyphenyl)-2-methylpropanenitrile

HRID 1382515노트

반응식

[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:11]2C=CC(O)=CC=2)([CH3:10])[CH3:9])=[CH:4][CH:3]=1.[C-]#[N:19].[C-]#N.[Na+]>>[C:11]([C:8]([C:5]1[CH:6]=[CH:7][C:2]([OH:1])=[CH:3][CH:4]=1)([CH3:9])[CH3:10])#[N:19]

참가 물질

반응물 3

HCID 5975Cyanide

HCID 6623Bisphenol A

HCID 8929Sodium Cyanide

생성물 1

HCID 144190652-(4-Hydroxyphenyl)-2-methylpropanenitrile

반응 조건

온도: 185 °C

실험 절차

A process wherein a solventless mixture of Bisphenol A and cyanide ion in the form of sodium cyanide is heated in a closed vessel to about 185° C. and maintained at that temperature for about 20 hours to produce 4-(1-cyano-1-methylethyl)phenol with a conversion of about 100 percent and a selectivity of about 80 percent based on Bisphenol A.

후처리

temperaturemaintained at that temperature for about 20 hours

출처 및 근거

ORD 기록: ord-f9c9e5ef7e3e4fa1bc2af1b3a31abc1c
출처 데이터셋: uspto-grants-1989_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04806673

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