Triphenylphosphine → HCID 21274172, 화합물

HRID 1383237노트

반응식

HRID 1383237 반응식
[O:1]([C:8]1[CH:9]=[C:10]([CH2:14][CH2:15][CH2:16][Br:17])[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:18]1([P:24]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(#N)C>[Br-:17].[O:1]([C:8]1[CH:9]=[C:10]([CH2:14][CH2:15][CH2:16][P+:24]([C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:11]=[CH:12][CH:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 11776TriphenylphosphineHCID 137698271-(3-Bromopropyl)-3-phenoxybenzene

생성물 1

HCID 21274172HCID 21274172, 화합물수율 75.9%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

Under nitrogen a mixture of 2.9 grams (0.01 mole) of 3-(3-phenoxyphenyl)propyl bromide and 2.9 grams (0.01 mole) of triphenylphosphine in 25 mL of acetonitrile was heated at reflux overnight. The solvent was evaporated under reduced pressure. Toluene was added to the residue, and this mixture was heated at reflux for 90 minutes during which a solid formed. Filtration yielded 4.2 grams of 3-(3-phenoxyphenyl)propyltriphenylphosphonium bromide, m.p. 198°-200° C.

후처리

  1. temperaturewas heated
  2. temperatureat reflux overnight
  3. customThe solvent was evaporated under reduced pressure
  4. additionToluene was added to the residue
  5. temperaturethis mixture was heated
  6. temperatureat reflux for 90 minutes during which a solid
  7. customformed
  8. filtrationFiltration

출처 및 근거

ORD 기록
ord-254420196a3449c482dbc9a9616c38ca
출처 데이터셋
uspto-grants-1989_02
특허 번호
US04808762

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