Hydrochloric Acid → 2,3-Diaminophenol--hydrogen chloride (1/2)

HRID 1384001노트

반응식

HRID 1384001 반응식
[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[OH:9].[ClH:10]>C(O)C>[ClH:10].[ClH:10].[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[OH:9]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 5799372,3-Diaminophenol

생성물 1

HCID 184017512,3-Diaminophenol--hydrogen chloride (1/2)

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
50 °C

실험 절차

In a 250 ml single neck round bottom flask was added 2,3-diaminophenol (10 g, 80.55 mmol) to ethanol (100 ml). This mixture was heated to 50° C. to achieve dissolution. The resulting solution is cooled to −5 to 0° C. and an excess of anhydrous hydrogen chloride gas was added to form a viscous slurry. The resulting mixture was stirred for two hours at ˜0° C., then filtered, and rinsed with chilled methanol (30 ml). The solvents were removed in vacuo and the residue was dried overnight.

후처리

  1. dissolutiondissolution
  2. temperatureThe resulting solution is cooled to −5 to 0° C.
  3. customto form a viscous slurry
  4. filtrationfiltered
  5. washrinsed with chilled methanol (30 ml)
  6. customThe solvents were removed in vacuo
  7. customthe residue was dried overnight

출처 및 근거

ORD 기록
ord-8db2d0d1e5914a8a9fe096d494e21526
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06255494B1

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