3-Aminopyridine → HCID 54032883, 화합물

HRID 1385098노트

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HRID 1385098 반응식
[CH:1]1([N:6]2[C:14]3[C:9](=[CH:10][CH:11]=[C:12]([C:15](Cl)=[O:16])[CH:13]=3)[C:8]([CH2:18][CH3:19])=[N:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:20][C:21]1[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=1>>[N:23]1[CH:24]=[CH:25][CH:26]=[C:21]([NH:20][C:15]([C:12]2[CH:13]=[C:14]3[C:9]([C:8]([CH2:18][CH3:19])=[N:7][N:6]3[CH:1]3[CH2:5][CH2:4][CH2:3][CH2:2]3)=[CH:10][CH:11]=2)=[O:16])[CH:22]=1

참가 물질

3

반응물 2

HCID 100093-AminopyridineHCID 15545850HCID 15545850, 화합물

생성물 1

HCID 54032883HCID 54032883, 화합물수율 34.2%

실험 절차

This compound was prepared according to the method of Example 15, using 58 mg (0.210 mmol, 1.0 equiv) 1-cyclopentyl-3-ethyl-1H-indazole-6-carbonyl chloride and 22 mg (0.231 mmol, 1.1 equiv) 3-aminopyridine as starting materials, to give 24 mg (34%) of white crystals: mp 133-135° C.; HRMS calcd for C20H22N4O+H: 335:1872. Found: 335.1900.

후처리

  1. customThis compound was prepared

출처 및 근거

ORD 기록
ord-304155de182c42aeaf2d146363720ea3
출처 데이터셋
uspto-grants-2001_07
특허 번호
US06262040B1

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